The most commonly abused prescription drugs varies from place to place. However, generally speaking, the top 10 most abused prescription drugs are: OxyContin Xanax Vicodin Suboxone Adderall Valium Percocet Ambien Fentanyl Klonopin The Blackberry CenterNestled in a tranquil setting just outside of Orlando, in Central Florida, our mental health facility provides patients with a safe place to reflect, reset and heal.